Ledger · 2026-08-29 · Biotechnology / Food Safety

Commercial Production of Pediocin PA-1 Biopreservative via Low-CapEx Fermentation

Cleared

This concept cleared all seven gates and every voiding sub-test.

Incumbent displacedNisin (E234)
Measured advantage22x lower IC50 against Listeria monocytogenes compared to Nisin (0.10-7.34 ng/mL vs 2.2-781 ng/mL)
Time to first revenue6 months
Gross margin at parity69.4%
Startup CapEx$185,000

The full analysis goes to the list

Mechanism, operating protocol with real conditions and yields, computed unit economics with a six-scenario stress test, the absence audit, and every resolved citation.

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Assessed 2026-08-29 against seven gates plus the voiding sub-tests. How the method works · Browse all concepts